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Clémence Léger

profil-pics
  • PhD Student
  • Clemence.Leger@u-bourgogne.fr
  • +33 3 80 39 32 27
  • 373
  • Laboratoire INSERM U1093
    Université de Bourgogne
    UFR Sciences de Santé
    7 Bd Jeanne d’Arc
    21079 Dijon CEDEX

PROFILE

Physiology and Neurosciences

2022 Master Biologie-Santé – parcours Signalisation Cellulaire et Moléculaire – Dijon
2020 Licence Biologie – Biologie Cellulaire et Physiologie – Dijon
2019 Master Biologie-Santé – parcours Signalisation Cellulaire et Moléculaire – Dijon
  • Title: Irisin and neuroplasticity
  • Supervisor: Anne TESSIER (UP)
  • Co-Supervisor: Aurore QUIRIÉ (PhD, IgE)
  • Research Topic: My research focuses on the muscle-brain dialogue during physical exercise, specifically the impact of the myokine “Irisin” on neuroplasticity. The main objective is to determine its modalities of secretion and its action on the brain.

PUBLICATIONS

Scientific articles in international or national peer-reviewed journals

2024
Chaney R, Leger C, Wirtz J, Fontanier E, MÈloux A, QuiriÈ A, Martin A, Prigent-Tessier A, Garnier P Cerebral Benefits Induced by Electrical Muscle Stimulation: Evidence from a Human and Rat Study. Int J Mol Sci. 2024;25(3). doi: 10.3390/ijms25031883. PMID: 38339161.
Leger C, QuiriÈ A, MÈloux A, Fontanier E, Chaney R, Basset C, Lemaire S, Garnier P, Prigent-Tessier A Impact of Exercise Intensity on Cerebral BDNF Levels: Role of FNDC5/Irisin. Int J Mol Sci. 2024;25(2). doi: 10.3390/ijms25021213. PMID: 38279218.
2023
Cefis M, Chaney R, Wirtz J, MÈloux A, QuiriÈ A, Leger C, Prigent-Tessier A, Garnier P Molecular mechanisms underlying physical exercise-induced brain BDNF overproduction. Front Mol Neurosci. 2023;16:1275924. doi: 10.3389/fnmol.2023.1275924. PMID: 37868812.